WHAT IS EpiOtic® SIS?

EpiOtic® SIS. Gentle Yet Powerful.

  • A gentle, pH balanced ear cleanser which aids in the removal of wax and reduces odour1,3
  • Kills and inhibits the growth of infectious agents associated with otitis externa1,2
  • Facilitates the delivery of prescribed ear medications1,2
  • Proven microbicidal action against Australian clinical isolates, including MRSP2

RECOMMENDED FOR

  • For ear cleansing or for the management or prevention of otitis externa in dogs.

WHY CHOOSE EPIOTIC® SIS?

  • Gentle pH Neutral Micellar Solution: pH balanced, non-irritating formula which helps to remove cellular debris and wax, correct excessive moisture in the ear canal and emulsify wax, aiding its removal. Optimal tolerance, for use in dogs.1,3

  • Antimicrobial action: Kills and inhibits the growth of infectious agents associated with otitis externa. Antimicrobial against bacteria and yeast representing the most common causes of canine otitis externa. Facilitates the delivery of prescribed ear medications.1,2

  • SIS (Skin Innovative Science) Technology: Ingredients that work together to limit microbial adherence to the skin surface, and stimulate the skin’s natural defence mechanisms.4-8

  • Anti-Odour Technology: Neutralises unpleasant smells resulting in a statistically significant decrease in odour. Also has a mild citrus aroma which keeps ears smelling fresh.1,3

ACTIVE CONSTITUENTS:

  • 5 mg/mL Disodium EDTA
  • 2 mg/mL Salicylic Acid

DOSAGE & DIRECTIONS FOR USE:

A veterinary examination to assess the ears and general health of the dog is recommended before use. EpiOtic SIS can be applied up to twice daily or as directed by a veterinarian. For routine use: aim the tip of the bottle into the ear canal and squeeze to apply solution. Gently massage the ear.

STORAGE

Store in a dry place at room temperature. Keep the seal tightly closed.

PACK SIZES

  • 237 mL
  • 500 mL

 

References:

  1. Epiotic SIS APVMA Approval No. 91291/131613.
  2. Chan W.Y, Knowles A.G and Trott D.J, 2020, In vitro antimicrobial activity of Epiotic SIS and Easotic against pathogens associated with canine otitis externa in Australia, Veterinary Dermatology, Vol 31 (Suppl. 1), p78.
  3. Virbac data on efficacy for APVMA registration.
  4. McEwan, N.A., Kelly, R., Woolley, K., Reme, C.A., Gatto, H. & Nuttall, T.J. (2007). Sugar inhibition of Malassezia pachydermatis to canine corneocytes, Veterinary Dermatology, 18(3), 187-188.
  5. McEwan, N.A., Reme, C.A., Gatto, H. & Nuttall, T.J. (2006). Sugar inhibition of adherence by Staphylococcus intermedius to canine corneocytes, Veterinary Dermatology, 17(5), 358.
  6. McEwan, N.A., Reme, C.A., Gatto, H. & Nuttall, T.J. (2008). Monosaccharide inhibition of adherence by Pseudomonas aeruginosa to canine corneocytes, Veterinary Dermatology, 19, 221-225.
  7. Santordo, D. et al. (2016). Evaluation on the effects of 0.1% Peumus boldus leaf and Spiraea ulmaria plant extracts on bacterial colonization in canine atopic dermatitis: a preliminary randomised, controlled, double-blinded study. Accepted for communication at the WCVD 2016, Bordeaux, France.
  8. Marsella, R., Athrens, K., Vesney R, & Santano, D. (2013). Evaluation of the in vitro effect of plant extracts on the production of antimicrobial peptides and inflammatory markers in canine keratinocytes: a pilot study, Veterinary Dermatology, 24 308 – 309.
SKU EPI-500
Brand Epi-otic
Shipping Weight 0.7000kg
Shipping Width 0.070m
Shipping Height 0.070m
Shipping Length 0.260m
Shipping Cubic 0.001274000m3

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